In this experiment, students will synthesize and characterize one of three Ag(I) cyanoximate complexes as potential antimicrobial agents for use in dental implants. This experiment combines simple ligand synthesis, metalation and characterization, and a biomedical application. The complexes are both air and light stable.
This is the procedure for a Fe(III) catalyzed synthesis of aspirin, an alternative to the traditionally sulfuric acid catalyzed synthesis of aspirin. The prep compares and contrasts the Bronsted acid catalyzed esterification reaction with a Lewis acid iron (III) catalyzed pathway. This can be used in different courses at different levels, but is it written for a general/intro level chemistry course.
In this literature discussion, students are asked to read an article describing a type of dual catalytic system in which the synergistic combination of photoredox catalysis and nickel catalysis provides a general method that would exploit naturally abundant, inexpensive organic molecules as coupling partners. This paper addresses several green chemistry principles and serves as a great literature example for teaching organometallic chemistry or green chemistry course.
The following paper will be given to the students to study at home along with the questions in the attached document. Students will be allowed to discuss their answers in small groups and refine their answers, before the corresct answer is revealed.
The students will not need to see the actual spectra that are in the SI to be able to address the given questions, the spectra can be projected to the class when the answers of the student groups are discussed
Origins of Enantioselectivity during Allylic Substitution Reactions Catalyzed by Metallacyclic Iridium Complexes.
The following paper will be given to the students to read at home along with the questions in the attached document. Students will be allowed to discuss their answers in small groups and refine their answers, before the corresct answer is revealed.
Origins of Enantioselectivity during Allylic Substitution Reactions Catalyzed by Metallacyclic Iridium Complexes.
J. Am. Chem. Soc., 2012, 134 (19), pp 8136–8147
DOI: 10.1021/ja212217j
We have prepared a YouTube video demonstrating a visually accessible kinetic isotope effect in the Cr(VI) oxidation process, a reaction commonly encountered in introductory organic chemistry. The demo provides students with an opportunity to see an isotope effect and then understand how it can be used to provide mechanistic evidence for the identification of a rate-determining reaction step.
These 6 slides introduce the nomenclature used to describe the stereochemistry of various polypropylenes (PPs) that can be synthesized by metallocene-catalyzed polymerizations. Although PP is the specific polymer discussed, the nomenclature applies to other alpha-olefin polymerizations.
This project is designed to develop the research skills that are required to tackle projects that are larger and more complex than those encountered in first and second year chemistry courses. The lab is an integrated project-oriented laboratory including synthesis and the use of instrumental techniques such as UV-Visible and infrared, 1H-NMR and 13C-NMR spectrometry, chromatography (HPLC, TLC) and cyclic voltammetry.
A simple coin-flipping game to help students understand the origin of spin/spin splitting in 1H NMR.
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