Comprehensive literature reading assignment on platinum-based anticancer agents
Students read two review articles and one research article on platinum-based cancer therapeutic agents. These articles compresentively discuss various aspects of these drug agents such as discovery, synthesis, mode of function. Students read the articles and use the knowledge on coordination chemistry (structure, reactivity, bonding, etc.) to explain the information included in the articles.
References:
Inorganic Chemistry
From syllabus:
Chem 165 2018
This is a collection of LOs that I used to teach a junior-senior seminar course on organometallics during Fall 2018 at Harvey Mudd College. There were a total of 9 students in the course. The Junior student (there was only one this year) was taking 2nd semester organic concurrently and had not takein inorganic (as is typical).
1FLO: PCET and Pourbaix
This set of questions is based on a single figure from Rountree et al. Inorg. Chem. 2019, 58, 6647. In this article (“Decoding Proton-Coupled Electron Transfer with Potential-pKa Diagrams”), Jillian Dempsey’s group from the University of North Carolina examined the mechanism by which a nickel-containing catalyst brings about the reduction of H+ to form H2 in non-aqueous solvent.
Triphenylphosphine: Transformations of a Common Ligand
This experiment tasks students with preparing triphenylphosphine sulfide, and the corresponding I2 adduct, then characterizing these products using common instrumental methods. Students are asked to consider MOs and tie this to their Lewis bonding depiction for the final product. This discussion is supported by WebMO calculations and tied to the experimental data obtained by the student.
Intermediate Inorganic Chemistry, Spring 2020
An introduction to the chemistry of inorganic compounds and materials. Descriptive chemistry of the elements. A survey of Crystal Field Theory, band theory, and various acid-base theories. Use of the chemical and scientific literature. Introduction to the seminar concept.
Inorganic Chemistry
Theoretical and descriptive inorganic/bioinorganic chemistry. Examines molecular structure and other properties of crystals, coordination compounds, and organometallic compounds. Topics include the roles of metal complexes as acids and bases, in oxidation-reduction reactions, and in biochemical systems. Laboratory in which main group and transition metal compounds are synthesized and studied. This course counts towards the Writing Across the Curriculum requirement.
Inorganic Chemistry
Modern theories of bonding and structure, spectroscopy, redox chemistry, and reaction mechanisms. Coordination compounds, organometallic clusters, and catalysis.
Inorganic Chemistry I
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