My group works on the asymmetric hydroamination reaction using chiral amino-alcohol ligands.  The ligands are prepared in a few steps from naturally occurring amino acids.  We have observed enantiomeric excesses of about 16% for the ring closing of 2-methyl-2,3-heptylamine (1,1-dimethyl-3-propylamino-allene...hmm, I wish we had a structure tool on the site...)