Synthesis and Migratory-Insertion Reactivity of CpMo(CO)3(CH3): Small-Scale Organometallic Preparations Utilizing Modern Glove-Box Techniques

Submitted by Matt Whited / Carleton College on Mon, 08/26/2013 - 14:22
Description

This laboratory experiment spans three weeks and introduces advanced undergraduates to modern small-scale synthesis techniques involving an inert-atmosphere glove box.  The robust syntheses transform [CpMo(CO3]2 into the methylated CpMo(CO)3(CH3) and examine the phosphine-induced migratory insertion to form various Cp-supported Mo(II) acetyl complexes.  At each step in the synthesis, a combination of IR and multinuclear (1H, 13C, and 31P) NMR spectroscopies allow students to assess the purity of their products and

Literature summary through student presentation - free choice of topic.

Submitted by Cameron Gren / University of North Alabama on Wed, 06/26/2013 - 07:59
Description

(1) Student choses and reads a journal article of his/her choice that is related to a topic we have discussed during the semester. (i.e. atomic structure, MO theory, group theory, solid state structure, band theory, coordination chemistry, organometallics, catalysis). Suggested journals include, but are not limited to JACS, Inorg. Chem., Organometallics, Angew. Chem., JOMC, Chem. Comm.)

(2) Student answers the following questions regarding their chosen article:

    (a) Describe, in 1 or 2 sentences the goal of this work. 

A Visual Isotope Effect (a YouTube video)

Submitted by Dan O'Leary / Pomona College on Wed, 04/24/2013 - 17:46
Description

We have prepared a YouTube video demonstrating a visually accessible kinetic isotope effect in the Cr(VI) oxidation process, a reaction commonly encountered in introductory organic chemistry. The demo provides students with an opportunity to see an isotope effect and then understand how it can be used to provide mechanistic evidence for the identification of a rate-determining reaction step.

Online Courses Directory

Submitted by Adam Johnson / Harvey Mudd College on Mon, 04/01/2013 - 07:41
Description

This website is a free and comprehensive resource that is a collection of open college courses that spans videos, audio lectures, and notes given by professors at a variety of universities. The website is designed to be friendly and designed to be easily accessed on any mobile device.

Metal-Ligand Multiple Bonds and Frustrated Lewis Pairs

Submitted by Matt Whited / Carleton College on Wed, 10/10/2012 - 14:40
Description

This is a literature-based activity that focuses on a review I recently published as part of a thematic series on C-H activation.

The review highlights similarities between the newly discovered frustrated Lewis pairs and polarized metal-ligand multiple bonds.  There are many ways to use the review, but the attached set of questions focuses on drawing analogies among seemingly diverse types of reactivity using frontier-molecular-orbital considerations.

Identifying Organometallic Reaction Classes in a Catalytic Cycle

Submitted by Nancy Williams / Scripps College, Pitzer College, Claremont McKenna College on Tue, 08/28/2012 - 19:01
Description

This contains three parts: A "Pre-Read" section for students to read before coming to class, an in-class worksheet to be worked in groups, and instructor keys for the worksheet.

The purpose of this exercise is to familiarize and give practice with identifying major classes of reaction (oxidative addition, etc.) in an organometallic catalytic cycle. After this exercise, students should be able to do the same for a new catalytic cycle provided by the instructor on a homework set or exam.

Alkyne Semihydrogenation with Niobium(II) Imido Complexes: Exploring An Unconventional Hydrogenation Mechanism

Submitted by Matt Whited / Carleton College on Thu, 08/09/2012 - 11:30
Description

This is a literature discussion based on an interesting Bergman/Arnold paper utilizing d2 niobium imido complexes for the semihydrogenation of arylalkynes to Z-alkenes.  The mechanism is quite unusual, and I found it to be an interesting paper to discuss after we had talked about the classical hydrogenation mechanisms (typically observed for late transition metals).  The students should come into the discussion understanding fundamental reaction mechanisms (including σ-bond metathesis), and it's helpful if they are somewhat familiar with mono- and dihydride mech

Soluble Methane Monooxgenase Spectroscopy

Submitted by Gerard Rowe / University of South Carolina Aiken on Fri, 07/20/2012 - 09:37
Description

Determining the reactive intermediates in metalloenzymes is a very involved task, and requires drawing from many different spectroscopies and physical methods.  The facile activation and oxidation of methane to produce methanol is one of the "holy grails" of inorganic chemistry.  Strategies exist within materials science and organometallic chemistry to activate methane, but using the enzyme methane monooxygenase, nature is able to carry out this difficult reaction at ambient temperatures and pressures (and in water, too!).

Dioxygen Activation in Non-heme Iron Enzymes

Submitted by Gerard Rowe / University of South Carolina Aiken on Fri, 07/20/2012 - 09:26
Description

This lecture provides a short introduction to the other half of biological iron chemistry:  enzymes that do not contain a porphyrin group that ligates the iron atom.  There are several important applications for non-heme iron in cells, both mammalian and bacterial.  Oxygen activating non-heme iron enzymes fall into a few basic categories and includes mononuclear iron monooxygenases and dioxygenases, and binuclear iron monooxygenases. The requirements to activate and utilize dioxygen will be given.

Electrocatalysis and Proton Reduction

Submitted by Matt Whited / Carleton College on Thu, 07/19/2012 - 16:46
Description

These slides provide a brief introduction to the concept of electrocatalysis using the glyoximato cobalt catalysts for hydrogen production recently examined by Peters, Gray, and others.  They provide a suitable introduction to the topic for students interested in reading the primary literature on these topics.

Subscribe to Reaction mechanisms