This literature discussion is based on a paper by Karen Goldberg (J. Am. Chem. Soc., 1995, 117, 6889-6896). In this early paper by Goldberg, she studied the reductive elimination of ethane and methyl iodide from dppePtMe3I. The paper is well written, and approachable for undergraduates. It shows a real, interesting application of thermodynamic and kinetic methods to the study of a problem in mechanistic chemistry. The experimental details are complete, and this paper would serve as a good review of kinetics, thermodynamics, and organometallic reaction mechanisms.
This LO presents a series of guided reading questions that help a student approach some of the material presented in the paper in a more thorough way. It asks students to derive equations and understand how experimental data can be combined into a reaction coordinate free energy diagram. The LO is suitable for junior or senior undergraduates in an organometallics course or unit within an inorganic course.
An update and correction was made to the LO in April 2018. Questions 7 and 8 in the learning object have students address the point of the differing M-C and M-I bonds. For the purposes of understanding what was written at the time, the questions are still valid, but the conclusions drawn in the paper about M-X bond strengths are not. For more information, see the "faculty only" file entitled "Goldberg Update 201804."
upon completing this LO students should be able to
1. demonstrate where thermodynamic parameters come from in a reaction coordinate free energy diagram
2. derive complex rate equations using the steady state approximation
3. describe the principle of microscopic reversibility
4. gain a deeper appreciation for the experimental methods (thermodynamic and kinetic) used in mechanistic chemistry
I used this LO as a guided reading handout for a senior-level organometallics class. The questions and the paper were provided to the students a week in advance and the in-class activity was a student-led discussion of the paper.